"This is against the Cambodians who went to vote to decide their own fate," Phay Siphan told Reuters.
Newspaper headlines in Cambodia on Monday greeted Hun Sen's victory.
Polling stations visited by Reuters in the capital, Phnom Penh, were quiet on Sunday and some voters said they voted because not doing so would land them in trouble.
"The flawed elections, which excluded the country's principal opposition party, represent the most significant setback yet to the democratic system enshrined in Cambodia’s constitution," Sanders said. The election campaign was marred by threats from national and local leaders, she said.
China has poured billions of dollars in development assistance and loans into Cambodia through bilateral frameworks and its Belt and Road initiative to build a new Silk Road.
"The CPP won 77.5 percent of the votes and won all the parliamentary seats," CPP spokesman Sok Eysan told Reuters by telephone. "The other parties won no seats."
"29 July 2018 marked the death of democracy in Cambodia, a dark new day in recent history," said CNRP vice president Mu Sochua. "The result announced by the CPP and the National Election Committee must be fully rejected by the international community."
Some independent media were targeted by Hun Sen and his allies in a pre-election crackdown.
Cambodia woke to another chapter of rule by strongman Hun Sen a day after an election that was heavily criticised by rights groups, the United States and other Western countries.
Critics say the election was a backward step for democracy in Cambodia following the dissolution last year of the main opposition Cambodian National Rescue Party (CNRP) and the jailing of its leader, Kem Sokha, on treason charges.
White House Press Secretary Sarah Sanders said in a statement Sunday's vote "failed to represent the will of the Cambodian people".
More than 82 percent of those registered to vote cast a ballot, according to the National Election Committee. Turnout was 90 percent in the 2017 local election and 69.61 percent in the previous general election in 2013.
The European Union has threatened Cambodia with economic sanctions.
"The United States will consider additional steps to respond to the elections and other recent setbacks to democracy and human rights in Cambodia, including a significant expansion of the visa restrictions announced on December 6, 2017," Sanders said.
"We hope that the international community can provide constructive help for Cambodia to remain stable and achieve development."
At the Kapkor Market in Phnom Penh, Meas Sinuon, 60, said she was pleased with Sunday's result.
"CPP Dominates Election: Unofficial results show ruling party will increase its majority in the National Assembly," said the pro-government Khmer Times newspaper.
Unofficial election results are expected in mid-August.
The United States has imposed visa curbs on some Cambodian government members over a crackdown on critics and levied sanctions in June on a high-ranking official close to Hun Sen.
'DEATH OF DEMOCRACY'
The CNRP also called on the international community to reject the result of the election.
"I believe that the Cambodian parliament election is an internal matter for Cambodia," Foreign Ministry spokesman Geng Shuang told a daily news briefing in Beijing on Monday.
The CNRP had called on voters to boycott the election but authorities warned anyone doing so would be seen as a traitor.
"This government has done good things already," she said as she shopped for groceries. "But I want the new government to do more to help the people."
The White House said it would consider steps, including an expansion of visa restrictions placed on some Cambodian government members, in response to "flawed elections" in which there was no significant challenger to Hun Sen.
PHNOM PENH, REUTERS -- Prime Minister Hun Sen's ruling Cambodian People's Party (CPP) said on Monday it had won all 125 parliamentary seats up for grabs in a general election a day earlier that critics said was neither free nor fair.
Government spokesman Phay Siphan said the White House statement was an attempt to intimidate Cambodia.
Former CNRP president Sam Rainsy, who lives in exile, said the election was a "hollow" victory for Hun Sen, a former Khmer Rouge commander who has ruled Cambodia for nearly 33 years.
Even as the West criticised the process, Hun Sen still has one important ally, China, which offered warm congratulations for a smooth election.
Another voter, a Phnom Penh tuk-tuk driver who declined to be identified, described the result as "same".
CNRP Deputy Director of Foreign Affairs Monovithya Kem told a news conference in Jakarta on Monday the party welcomed the White House statement and hoped others would follow suit.